منابع مشابه
Dietary Fat and the Risk of Colorectal Cancer1
The relationship between the intake of dietary fat and subse quent colorectal cancer during a 15-year follow-up was investi gated in 7074 men of Japanese ancestry, 45 to 68 years old and living in Hawaii. Data on fat intake were obtained by 24-hr recall records at base-line examination. We found a statistically signif icant, negative association between colon cancer and the intake of saturated ...
متن کاملCholesterol Excretion and Colon Cancer1
Populations consuming diets high in fat and cholesterol exhibit a greater incidence of colon cancer than those consum ing less fat and cholesterol. Lowering elevated serum choles terol levels experimentally or clinically is associated with in creased large-bowel tumorigenesis. Thus, cholesterol lost to the gut, either dietary or endogenously synthesized, appears to have a role in large-bowel ca...
متن کاملDietary fat and risk of breast and colon cancer.
In the past decade, a substantial number of case-control and cohort studies have addressed the relationship between fat intake and the incidence of colon and breast cancer. Among the more recent case-control studies of colon or rectal cancer, relatively consistent findings have emerged indicating positive relationships with animal fat or red meat intake. In two large recent prospective studies,...
متن کاملCalcium, Vitamin D, and Colon Cancer1
Calcium contributes to the progression of epithelial cells through all phases of the proliferative cycle and into stages of cell differentiation; intracellular concentrations of calcium that are required for cell renewal, however, are lower than those required for epithelial-cell differentiation. These effects of calcium are modulated by interactions with 1,25-dihydroxy-vitamin I>.. phosphate, ...
متن کاملSome MethodologicalIssuesin EpidemiologicalStudiesof Fat and Cancer1
Three types of approach to the study of the possible rela tionship between fat and cancer are discussed, namely, cor relational, case-control, and cohort studies. The advantages and limitations of each method are analyzed, and it is empha sized that a necessary prerequisite to direct observational studies In humans is the development of a satisfactory and uniform method of a diet assessment. De...
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ژورنال
عنوان ژورنال: JNCI: Journal of the National Cancer Institute
سال: 1975
ISSN: 1460-2105,0027-8874
DOI: 10.1093/jnci/54.1.7